Vitamin D Receptor anticorps (AA 128-427)

N° du produit ABIN6150080

Cet anticorps Lapin Polyclonal détecte spécifiquement Vitamin D Receptor dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour Vitamin D Receptor anticorps (AA 128-427) (ABIN6150080)

Antigène: Vitamin D Receptor (VDR)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Vitamin D Receptor est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Vitamin D Receptor anticorps

Épitope: AA 128-427

Séquence: QQRIIAILLD AHHKTYDPTY SDFCQFRPPV RVNDGGGSHP SRPNSRHTPS FSGDSSSSCS DHCITSSDMM DSSSFSNLDL SEEDSDDPSV TLELSQLSML PHLADLVSYS IQKVIGFAKM IPGFRDLTSE DQIVLLKSSA IEVIMLRSNE SFTMDDMSWT CGNQDYKYRV SDVTKAGHSL ELIEPLIKFQ VGLKKLNLHE EEHVLLMAIC IVSPDRPGVQ DAALIEAIQD RLSNTLQTYI RCRHPPPGSH LLYAKMIQKL ADLRSLNEEH SKQYRCLSFQ PECSMKLTPL VLEVFGNEIS

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 128-427 of human VDR (NP_000367.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Vitamin D Receptor

Antigène: Vitamin D Receptor (VDR)

Autre désignation: VDR

Classe de substances: Chemical

Sujet: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins.,VDR,NR1I1,PPP1R163,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,VDR

Poids moléculaire: 48 kDa/53 kDa

ID gène: 7421

UniProt: P11473

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway